Longevity & Wellness

NAD+ Therapy: What It Is, What It Costs, and Who It's For

NAD+ injectable therapy explained — how it supports mitochondrial energy production, what it costs, and how Prolong Health's licensed providers determine if it's right for you.

What NAD+ Actually Is

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme every cell in your body uses for energy metabolism. It works inside your mitochondria — the part of the cell responsible for producing energy — where it plays a central role in the electron transport chain and ATP production.[1] Research on whether NAD+ levels decline with age is more nuanced than often claimed: several studies show tissue-specific declines (notably in blood and brain), while the picture across the body as a whole is still being studied.[2] Interest in NAD+ has grown alongside broader interest in mitochondrial health and longevity.

NAD+ therapy delivers it directly via injection, rather than through oral supplements.

Why Injection Instead of Oral

Oral NAD+ and its precursors are broken down by digestion before much reaches your bloodstream — research puts oral bioavailability around 5-15%, compared to close to 100% for injection, which bypasses the digestive process entirely.[3] Worth being direct about the limits of that data, though: higher blood NAD+ levels haven't been shown on their own to guarantee better outcomes — bioavailability and results aren't the same thing.

Who NAD+ Therapy Is For

NAD+ injectable therapy is typically sought out by people focused on energy, recovery, or general wellness support as part of a longevity-focused routine. It isn't a treatment for a specific diagnosed condition — it's a wellness therapy, and whether it's appropriate for you depends on your individual health history. That's why every Prolong Health patient goes through a real intake and provider review before starting.

What NAD+ Therapy Costs

Through Prolong Health, NAD+ injectable therapy starts at $225/month. Glutathione injectable therapy — often paired with NAD+ as an antioxidant-focused complement — starts at $189/month. Prolong Health is cash-pay, so the price reflects your full evaluation and treatment cost, with no insurance billing or hidden fees.

NAD+ vs. Glutathione

NAD+ supports cellular energy metabolism. Glutathione is an antioxidant. Some patients pursue one, some pursue both — your provider can help you decide what fits your goals during your evaluation.

How to Get Started

Complete an intake, get reviewed by a licensed provider, and if appropriate, start treatment.

Start Your Longevity & NAD+ Evaluation